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Xanthogranulomatous osteomyelitis : ウィキペディア英語版 | Xanthogranulomatous osteomyelitis
Xanthogranulomatous osteomyelitis (XO) is a peculiar aspect of osteomyelitis characterized by prevalent histiocytic infiltrate and foamy macrophage clustering.〔Rosai J(2004). Rosai and Ackerman's Surgical Pathology. Philadelphia, Mosby, p. 2142.〕 ==Clinical picture== As of 2011 five cases had been reported, involving rib, tibial epiphysis, ulna, distal tibia and femur. Young individuals are prevalently affected but one case involved a 50-year-old woman. Pain, swelling of possibly long duration, fever and increased ESR are some of the main clinical findings. X-ray examination shows lytic foci with sclerotic margins.〔Cozzutto C (1984) Xanthogranulomatous osteomyelitis. Arch Pathol Lab Med 108:973-976.〕〔Vankalakunti M, Saikia UN, Mathew M, Kang M (2007). Xanthogranulomatous osteomyelitis of ulna mimicking a neoplasm. World J Surg Oncol 5(46):1-4.〕〔Kashani MM, Zakerian BZ, Shayan K, Riyasi F (2010). Xanthogranulomatous osteomyelitis of femur. Iran J Orthop Surg 8(4):187-190.〕〔Kamat G, Gramapuroit V, Shettar C, Myageri A(2011). Xanthogranulomatous osteomyelitis presenting as swelling in right tibia. Case report. Case Rep Pathol, in press.〕 A neoplastic process can be suspected.
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